Enzymes may be simple proteins or complex enzymes. A complex enzyme contains a non-protein part, called a prosthetic group (co-enzymes). Coenzymes are heat stable low molecular weight organic compound. The combined form of protein and the co-enzyme are called as holo-enzyme. The heat labile or unstable part of the holo-enzyme is called as apo-enzyme. The apo-enzyme gives necessary three-dimensional structures required for the enzymatic chemical reaction. Co-enzymes are very essential for the biological activities of the enzyme. Co-enzymes combine loosely with apo-enzyme and are released easily by dialysis. Most of the co-enzymes are derivatives of vitamin B complex group of substance. One molecule of the co-enzyme with its enzyme is sufficient…