• Biochemistry

    Krebs (Citric Acid) Cycle

    It is also known as TriCarboxylic Acid (TCA) cycle.  In prokaryotic cells, the citric acid cycle occurs in the cytoplasm; in eukaryotic cells, the citric acid cycle takes place in the matrix of the mitochondria. The cycle was first elucidated by scientist “Sir Hans Adolf Krebs” (1900 to 1981). He shared the Nobel Prize for physiology and Medicine in 1953 with Fritz Albert Lipmann, the father of ATP cycle. The process oxidises glucose derivatives, fatty acids and amino acids to carbon dioxide (CO2) through a series of enzyme controlled steps. The purpose of the Krebs Cycle is to collect (eight) high-energy electrons from these fuels by oxidising them, which are transported…


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